Designed for Genomic Excellence

VE3’s Genomix is a secure, cloud-based platform designed for clinical and research genomics. It supports NHS Secure Data Environments and global standards, combining data management, AI-driven insights, and flexible workflows in one place. From rare disease diagnostics to multi-omics research, Genomix helps teams work faster, smarter, and together.

GenomiX brings everything together in one seamless platform

Managing large volumes of raw sequencing data
Integrating fragmented data from LIMS, EHRs, and research systems
Supporting complex multi-omics (DNA, RNA, epigenetics) pipelines
Automating and reproducing containerised workflows
Accelerating clinical interpretation and reporting
Standardising diverse genomic formats and annotations
Ensuring data security and compliance (NHS DSPT, GDPR, HIPAA)
Facilitating cross-institution collaboration

Unlock The Value of Genome Data

VE3 Genomix is the platform purpose-built to unify NHS-grade clinical genomics, flexible bioinformatics research, and AI-powered analysis. All delivered through a flexible, compliant, and scalable cloud architecture. A composable architecture designed around flexibility, compliance, and performance: 

API-First

Well-documented RESTful APIs and SDKs for integration, automation, and customisation

Data Fabric

Multi-tiered storage (object, file, archive) with lifecycle automation and replication 

Workflow Engines

Native support for Nextflow, WDL, CWL, and Snakemake 

Container-Native

Supports Docker, Singularity, and container orchestration via Kubernetes

Cloud-Agnostic

Deployed on AWS, Azure, or GCP based on NHS alignment or client preference

Everything You Need, Built In

Secure, cloud-native orchestration and storage for genomics workflows 

01. Data Ingestion

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Real-time ingestion from NGS instruments, LIMS, CROs.
Formats: FASTQ, BAM, CRAM, BCL, VCF, BED, GFF, TSV/CSV.
Multi-omics: RNA-Seq, ChIP-Seq, methylation, liquid biopsy.
BYOB (Bring Your Own Bucket) model for storage with lifecycle management.

02. Data Management

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Secure transfer (SFTP, HTTPS, Aspera)
Full input/output/reference format support
Tiered/hybrid storage (hot, cold, archive) with lifecycle automation
Metadata management and ontology-based harmonisation for multi-site research

03. Integrated Analysis

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Tools for experts (JupyterLab, APIs) and non-experts (dashboards)
Visualisation: QC trends, pathway enrichment, mutation heatmaps
AI/ML: Integrated with Databricks, SageMaker, VSCode Online
Models: XGBoost, CNNs, BERT, DESeq2, edgeR, GSEA
Supports AI-assisted discovery for rapid cohort building and variant interpretation

04. Workflow Orchestration

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Supports Nextflow Tower, Cromwell, CWL, Snakemake
Accelerated via GPUs/FPGA with DRAGEN, Sentieon, DeepVariant
Reproducibility via Git versioning, CI/CD pipelines

05. Bioinformatics Tools

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Preconfigured: FastQC, Trim Galore, BWA-MEM, GATK, DESeq2
Custom/Bring-your-own: VEP, ANNOVAR, FreeBayes, Mutect2
Extensible via Python, R, Bash, compiled binaries
Facilitates high-throughput, federated-ready pipelines

06. Customisation & Integration

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REST APIs for EHRs, LIMS, CDPs, dashboards
Secure custom connectors for registries, databases
Role-based access and infrastructure security (IDS, VPC, WAF, MFA)
Supports seamless integration with multi-institution research workflows

07. Infrastructure

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Deployable in UK cloud, NHS tenancy, or customer-hosted
Support for hybrid setups (central + VPC per lab)
Auto-scaling compute with GPU/FPGA nodes
Zero-copy architecture for secure, high-performance access to large datasets

08. Advanced Features

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Git-based pipeline & dataset versioning
Secure notebooks-as-a-service
FHIR Genomics Adapter for NHS clinical interoperability
MatchX Data Federation for cross-institution metadata linkage
Supports AI-native and federated-ready workflows at scale

09. Collaboration & Access Control

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Role-based RBAC/ABAC at dataset/sample/study level
NHS Identity, Azure AD federation
Pre-signed links, audit logs, version tracking
PromptX multi-user collaboration with minimal friction

10. Data Governance & Security

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End-to-end encryption (AES-256, TLS 1.3)
Full audit trails, provenance tracking, tamper-proof logs
Certified for clinical use and aligned with NHS/NIST security standards
Designed to meet strict data sovereignty and zero-copy requirements

What You Get

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Accelerated Research

Streamlined workflows and powerful compute resources enable faster insights.

Enhanced Collaboration

Securely share data and collaborate with colleagues in a controlled environment. 

Regulatory Compliance

Ensure adherence to data privacy regulations and industry best practices. 

Cost-Effectiveness

Optimize resource utilization with elastic scaling and flexible pricing models. 