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VE3’s Genomix is a secure, cloud-based platform designed for clinical and research genomics. It supports NHS Secure Data Environments and global standards, combining data management, AI-driven insights, and flexible workflows in one place. From rare disease diagnostics to multi-omics research, Genomix helps teams work faster, smarter, and together.
Integrating fragmented data from LIMS, EHRs, and research systems
Automating and reproducing containerised workflows
Standardising diverse genomic formats and annotations
Facilitating cross-institution collaboration
Managing large volumes of raw sequencing data
Supporting complex multi-omics (DNA, RNA, epigenetics) pipelines
Accelerating clinical interpretation and reporting
Ensuring data security and compliance (NHS DSPT, GDPR, HIPAA)
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VE3 Genomix is the platform purpose-built to unify NHS-grade clinical genomics, flexible bioinformatics research, and AI-powered analysis. All delivered through a flexible, compliant, and scalable cloud architecture. A composable architecture designed around flexibility, compliance, and performance:
Secure, cloud-native orchestration and storage for genomics workflows
Data Ingestion
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Real-time ingestion from NGS instruments, LIMS, CROs.
Formats: FASTQ, BAM, CRAM, BCL, VCF, BED, GFF, TSV/CSV.
Multi-omics: RNA-Seq, ChIP-Seq, methylation, liquid biopsy.
BYOB (Bring Your Own Bucket) model for storage with lifecycle
management.
Data Management
Supports secure transfer (SFTP, HTTPS, Aspera).
Format support for input, output, and reference files.
Tiered/hybrid storage (hot, cold, archive) with lifecycle automation.
Metadata management and ontology-based harmonisation.
Integrated Analysis
Tools for experts (JupyterLab, APIs) and non-experts (dashboards).
Visualisation: QC trends, pathway enrichment, mutation heatmaps.
AI/ML: Integrated with Databricks, SageMaker, VSCode Online.
Models: XGBoost, CNNs, BERT, DESeq2, edgeR, GSEA.
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Workflow Orchestration
Supports Nextflow Tower, Cromwell, CWL, Snakemake.
Accelerated via GPUs/FPGA with DRAGEN, Sentieon, DeepVariant.
Reproducibility via Git versioning, CI/CD pipelines.
Bioinformatics Tools
Preconfigured: FastQC, Trim Galore, BWA-MEM, GATK, DESeq2.
Custom/Bring-your-own: VEP, ANNOVAR, FreeBayes, Mutect2.
Extensible via Python, R, Bash, compiled binaries.
Customisation & Integration
REST APIs for EHRs, LIMS, CDPs, dashboards.
Secure custom connectors for registries, databases.
Role-based access and infrastructure security (IDS, VPC, WAF, MFA).
Infrastructure
Deployable in UK cloud, NHS tenancy, or customer-hosted.
Support for hybrid setups (central + VPC per lab).
Auto-scaling compute with GPU/FPGA nodes.
Advanced Features
Git-based pipeline & dataset versioning.
Secure notebooks-as-a-service.
FHIR Genomics Adapter for NHS clinical interoperability.
MatchX Data Federation for cross-institution metadata linkage.
Collaboration & Access Control
Role-based RBAC/ABAC at dataset/sample/study level.
NHS Identity, Azure AD federation.
Pre-signed links, audit logs, version tracking.
Data Governance & Security
End-to-end encryption (AES-256, TLS 1.3).
Full audit trails, provenance tracking, tamper-proof logs.
Certified for clinical use and aligned with NHS/NIST security standards.
Streamlined workflows and powerful compute resources enable faster insights.
Securely share data and collaborate with colleagues in a controlled environment.
Ensure adherence to data privacy regulations and industry best practices.
Optimize resource utilization with elastic scaling and flexible pricing models.
Streamlined workflows and powerful compute resources enable faster insights.
Streamlined workflows and powerful compute resources enable faster insights
Streamlined workflows and powerful compute resources enable faster insights
Streamlined workflows and powerful compute resources enable faster insights
Streamlined workflows and powerful compute resources enable faster insights
Streamlined workflows and powerful compute resources enable faster insights
Fragmented, duplicate, or Customizable permissions for users and groups at the study, sample, and data level.
Detailed logging of data access, modifications, and user actions for compliance purposes.
Customizable permissions for users and groups at the study, sample, and data level.
Protect sensitive information through obfuscation and encryption techniques.
On-demand, scalable compute for batch and real-time analysis
Design and execute customizable, reproducible workflows for raw data processing and analysis.
Real-world clinical and research scenarios where GenomiX is making an impact
Fully managed in UK-hosted cloud environment (ISO/NHS compliant)
Hosted within NHS Secure Data Environments or NHS cloud tenancies
Customer-controlled environment with setup, training, and support from VE3
Centralised platform with distributed, secure lab-specific VPCs or tenants
Fully managed in UK-hosted cloud environment (ISO/NHS compliant)
Hosted within NHS Secure Data Environments or NHS cloud tenancies
Customer-controlled environment with setup, training, and support from VE3
Centralised platform with distributed, secure lab-specific VPCs or tenants
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